PATENTS

PATENTS

No.

Title of the Invention

Date

Patent No.

60

Sleep improvement method using Limosilactobacillus reuteri strain LM1063

2026.06.02

12,642,823

59

A PROBIOTIC COMPOSITION FOR IMPROVING WHEY PROTEIN PROTEOLYSIS, AUGMENTING AMINO ACID PRODUCTION, AND IMPROVING LACTOSE DEGRADATION ABILITY

2026.06.02

10-2974194

58

Probiotics complex composition with immunomodulatory and immune homeostasis property

2026.05.26

12,636,328

57

PROBIOTICS COMPLEX COMPOSITION WITH IMMUNOMODULATORY AND IMMUNE HOMEOSTASIS PROPERTY

2026.04.28

7857437

56

Probiotic composition for improving soy protein proteolysis and amino acid production activity

2026.04.14

12,599,641

55

Composition of stimulating immunity comprising Lactobacillus rhamnosus LM1019 and starter strains

2026.03.31

12,589,126

54

COMPOSITION FOR PREVENTING HAIR LOSS AND PROMOTING HAIR GROWTH COMPRISING POSTBIOTIC COMPONENTS FROM HEAT-TREAT LIMOSILACTOBACILLUS FERMENTUM LM1020

2026.03.30

7841773

53

LACTOBACILLUS CRYOPROTECTANT

2025.07.21

10-2838310

52

BIFIDOBACTERIUM MIXED STRAIN DERIVED FEMALE VAGINAL TRACT WITH INHIBITORY EFFECTS ON VAGINITIS CAUSING FUNGUS AND COMPOSITION INCLUDING THE SAME

2025.06.23

10-2825583

51

MIXED PROBIOTIC STRAINS AND COMPOSITION COMPRISING THE SAME FOR IMPROVING SARCOPENIA

2025.04.11

10-2796656

50

LACTIPLANTIBACILLUS PLANTARUM STRAIN LM1215 DERIVED FROM HEALTHY KOREAN WOMEN VAGINAL TRACT, AND COMPOSITION COMPRISING THE SAME

2025.02.28

10-2792146

49

MIXED BIFIDOBACTERIUM STRAINS WITH EXCELLENT PRODUCTIVITY AND ANTI-INFLAMMATORY ACTIVITY, AND THEIR USE

2025.02.20

10-2772627

48

A COMPOSITION COMPRISING LACTIPLANTIBACILLUS PLANTARUM STRAIN LM1001 ORIGINATED FROM KIMCHI HAVING EXCELLENT PROTEOLYSIS ABILITY

2025.02.06

10-2766074

47

HEAT-TREATED LACTIPLANTIBACILLUS PLANTARUM LM1123, ORIGINATED FROM KIMCHI, WITH EXCELLENT IMMUNE REACTION ENHANCEMENT, AND A METHOD FOR MANUFACTURING THE SAME

2024.12.03

10-2739956

46

A NOVEL STRAIN OF LACTOBACILLUS REUTERI LM1071 SEPARATED FROM BREAST MILK, AND COMPOSITION FOR RELIEVING PREMENSTRUAL SYNDROME COMPRISING THE STRAIN OR ITS CULTURE FLUID

2024.10.01

CN 115210360 B

45

METHOD OF MANUFACTURING HIGH DENSITY KILLED-LACTIC ACID BACTERIA USING MEMBRANE FILTER AND KILLED-LACTIC ACID BACTERIA MANUFACTURED BY THE METHOD

2024.10.01

ZL 201780085192.2

44

Novel Lactobacillus Fermentum LM1016 Strain, And Composition For Preventing Or Treating Cardiovascular Diseases

2024.09.10

CN 112272697 B

43

LACTOBACILLUS REUTERI LM1071 FROM BREAST MILK HAVING HIGH SAFETY AND INTESTINE ADHESIVE PROPERTY, AND COMPOSITION COMPRISING THE STRAIN OR ITS CULTURE FLUID

2024.07.12

CN 113355255 B

42

A NOVEL STRAIN OF LACTOBACILLUS REUTERI LM1071 SEPARATED FROM BREAST MILK, AND COMPOSITION FOR RELIEVING PREMENSTRUAL SYNDROME COMPRISING THE STRAIN OR ITS CULTURE FLUID

2024.07.08

JP.7517736

41

Probiotic composition for improving soy protein proteolysis and amino acid production activity

2024.04.09

10-2657370

40

Lactobacillus rhamnosus lm1019 strain, and composition for preventing and treating obesity or diabetes including same

2023.11.03

CN 111801413 B

39

Composition of stimulating immunity comprising Lactobacillus rhamnosus LM1019 and starter strains

2023.09.11

10-2578409

38

Composition for preventing hair loss and promoting hair growth comprising postbiotic components from heat-treat Limosilactobacillus fermentum LM1020

2023.09.11

10-2578662

37

Probiotics complex composition with immunomodulatory and immune homeostasis property

2023.07.20

10-2559527

36

A COMPOSITION FOR IMPROVING SLEEP OR MAINTAINING SOUND SLEEP CONTAINING LIMOSILACTOBACILLUS RUETERI LM1063 STRAIN AS AN ACTIVE INGREDIENT, AND ITS USE

2023.07.20

10-2559526

35

Method for preparing highly concentrated killed bacteria using membrane filter and killed bacteria prepared thereby

2023.06.27

US.11685896.B2

34

COMPOSITION FOR PREVENTION AND TREATMENT OF ATOPIC DERMATITIS COMPRISING BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS LM1017 DERIVED FROM KOREAN INFANTS

2023.06.27

US.11684642.B2

33

Cosmetic composition for skin whitening containing novel lactobacillus rhamnosus lm1011 as active ingredient

2023.06.02

CN.112702990.B

32

A COMPOSITION FOR IMPROVING COGNITIVE ABILITY CONTAINING LACTOBACILLUS ACIDOPHILUS LM1060 STRAIN AS AN ACTIVE INGREDIENT AND ITS USE

2023.06.01

10-2540559

31

Lactobacillus Rhamnosus LM1019 Strain And Composition For Preventing And Treating Obesity Or Diabetes Mellitus Comprising Same

2023.02.07

US.11571448.B2

30

A NOVEL STRAIN OF LACTOBACILLUS GASSERI LM1065 SEPARATED FROM BREAST MILK, AND COMPOSITION FOR RELIEVING PREMENSTRUAL SYNDROME COMPRISING THE STRAIN OR ITS CULTURE FLUID

2023.01.12

10-2489459

29

Novel Lactobacillus Fermentum LM1016 Strain, And Composition For Preventing Or Treating Cardiovascular Diseases

2022.10.14

10-2456356

28

Novel Lactobacillus Fermentum LM1016 Strain, And Composition For Preventing Or Treating Cardiovascular Diseases

2022.09.27

US.11453857.B2

27

Novel lactobacillus fermentum lm1016 strain, and composition for preventing or treating cardiovascular diseases

2021.10.07

JP.6956896.B2

26

A COMSMETIC COMPOSITION FOR ANTI-AGING COMPRISING HEAT-KILLED LACTOBACILLUS ACIDOPHILUS

2021.06.24

10-2270939

25

A Novel Strain of Lactobacillus Reuteri LM1071 Separated from Breast Milk, and Composition for Relieving Premenstrual Syndrome Comprising the Strain or Its Culture Fluid

2021.06.16

10-2268128

24

A Novel Strain of Bifidobacterium Longum LM1024 Derived from Korean Infants, and Composition for Relieving Premenstrual Syndrome Comprising the Strain or Its Culture Fluid

2021.06.16

10-2268125

23

A novel strain of Lactobacillus paracasei LM1014 separated from kimchi, and composition for relieving premenstrual syndrome comprising the strain or its culture fluid

2021.06.16

10-2268122

22

A novel strain of Lactobacillus fermentum LM1020 separated from fermented wheat, and composition for relieving premenstrual syndrome comprising the strain or its culture fluid

2021.06.16

10-2268124

21

A novel strain of lactobacillus reuteri LM1071 separated from breast milk, and composition for relieving premenstrual syndrome comprising the strain or its culture fluid

2021.06.16

10-2268128

20

Lactobacillus rhamnosus LM1019 and Composition for Preventing and Treating Obesity or Diabetes Mellitus Comprising the Same

2021.04.06

JP-6864784

19

Lactobacillus reuteri LM1071 from Breast Milk Having High Safety and Intestine Adhesive Property, and Composition Comprising the Strain or its Culture Fluid

2020.03.04

10-2136522

18

Composition for Prevention and Treatement of Atopic Dermatitis Comprising Bifidobacterium animalis subsp. lactis LM1017

2019.12.23

10-2136346

17

Skin-Whitening Cosmetic Compositioin Comprising Lactobacillus rhamnosus LM1011 Having Immunostimulating Activity

2020.01.31

10-2074383

16

Cosmetic Composition for Improving Wrinkles and Skin Elasticity Comprising Bifidobacterium animalis subsp. lactis LM1017 Having Immunostimulating Activity

2020.01.31

10-2074384

15

Lactobacillus fermentum LM1016 and Composition for Preventing or Treating of Inflammatory Diseases and Metabolic Diseases Comprising the Same

2019.09.09

10-2021883

14

Streptococcus thermophilus LM1012 and Composition for Preventing or Treating of Inflammatory Diseases and Metabolic Diseases Comprising the Same

2019.09.09

10-2021881

13

Method of Manufacturing Growth Medium for Lactic Acid Bacteria Using Membrane Filter and Growth Medium for Lactic Acid Manufactured by the Method

2019.06.12

10-1990388

12

Lactobacillus fermentum LM1016 and Composition for Preventing and Treating Cardiovascular Diseases Comprising the Same

2019.05.15

10-1980527

11

Method of Concentrating Killed-Lactic Acid Bacteria Using Membrane Filter

2019.01.24

10-1943862

10

Method of Adjusing the Size of Killed-Lactic Acid Bacteria Using Membrane Filter

2019.01.23

10-1943622

9

Composition Comprising Heat-Killed Lactobacillus plantarum LM1004 Having Immunostimulating Activity

2018.11.13

10-1919938

8

Lactobacillus paracasei LM1010 and Composition for Preventing and Treating Obesity or Diabetes Mellitus Comprising the Same

2018.06.26

10-1873239

7

Lactobacillus rhamnosus LM1019 and Composition for Preventing and Treating Obesity or Diabetes Mellitus Comprising the Same

2018.05.29

10-1864347

6

Method of Manufacturing High Density Killed-Lactic Acid Bacteria Using Membrane Filter and Killed-Lactic Acid Bacteria Manufactured by the Method

2017.11.01

10-1794635

5

Medium Composition for Culturing Lactic Acid Bacteria and Producing Method of Powder of Lactic Acid Bacteria Using the Same

2016.03.14

10-1604633

4

The Alcohol Resistant Strain of Lactic Acid Bacteria, Pediococcus acidilactici and Its Use

2014.01.03

10-1349692

3

Lactobacillus. sp. JNU2116 with antimutagenic activity

2012.12.24

10-1217029

2

Lactobacillus casei CJNU 0588 Stimulating the Growth of Bifidobacterium sp., Foods Containing the Bacterial Strain and the Method for Growth Stimulation of Bifidobacterium sp. Using the Strain

2011.06.03

10-1040686

1

A Antibacterial Composition Comprising an Extract of Ulva Lactuca

2008.08.11

10-0852744

THESIS

THESIS

No.

Title of the Invention

Journal / Year

33

Microbiome-Modulating Effects of Heat-Treated Lactiplantibacillus plantarum LM1004 and Its Enhancement of NK Cell Activity: Evidence from a Clinical Trial and a Simulated Human Intestinal Microbiome Ecosystem

Journal of Microbiolog and Biotechnology / 2026

32

Hypnotic and sleep-promoting effects of Limosilactobacillus reuteri LM1063 on pentobarbital-induced sleep and electroencephalogram analysis in mice

scientific reports / 2026

31

Lactiplantibacillus plantarum LM1001 Supplementation Attenuates Muscle Atrophy and Function Decline in Aged Mice

Nutrients / 2025

30

Protective Effects of a Bifidobacterium-Based Probiotic Mixture on Gut Inflammation and Barrier Function

Microbiol. Res. / 2025

29

Lacticaseibacillus rhamnosus LM1019 Enhances Natural Killer Cell Activity in Defined Adult Subsets: A Double-Blind, Placebo-Controlled Trial

Life / 2025

28

Effects of Lactiplantibacillus plantarum LM1215 on Candida albicans and Gardnerella vaginalis

Yonsei Med J Actions Search in PubMed
Search in NLM Catalog Add to Search.

/ 2024

27

Lactiplantibacillus plantarum LM1001 improves digestibility of branched-chain amino acids in whey proteins and promotes myogenesis in C2C12 myotubes

Food Sci Anim Resour / 2024

26

Heat-treated Limosilactobacillus fermentum LM1020 with menthol, salicylic acid, and panthenol promotes hair growth and regulates hair scalp microbiome balance in androgenetic alopecia: A double-blind, randomized and placebo-controlled clinical trial

J Cosmet Dermatol / 2024

25

Clinical efficacy of L. plantarum, L. reuteri, and Ped. acidilactici probiotic combination in canine atopic dermatitis

Korea Journal of Veterinary Service / 2024

24

Acid tolerance responses and their mechanisms in Lactiplantibacillus plantarum LM1001

Food Science and Biotechnology / 2024

23

Immune-Stimulating Potential of Lacticaseibacillus rhamnosus LM1019 in RAW 264.7 Cells and Immunosuppressed Mice Induced by Cyclophosphamide

Microorfanisms / 2023

22

Draft genome sequence and probiotic functional property analysis of Lactobacillus gasseri LM1065 for food industry applications

scientigic reports / 2023

21

Synergistic antidepressant-like effect of n-3 polyunsaturated fatty acids and probiotics through the brain-gut axis in rats exposed to chronic mild stress

The Journal of Nutritional Biochemistry / 2023

20

Heat-treated Pediococcus acidilactici LM1013-mediated inhibition of biofilm formation by Cutibacterium acnes and its application in acne vulgaris: A single-arm clinical trial

journal of Cosmetic Dermatology / 2023

19

Multi-Species Probiotic Strain Mixture Enhances Intestinal Barrier Function by Regulating Inflammation and Tight Junctions in Lipopolysaccharides Stimulated Caco-2 Cells

Microorganisms. / 2023

18

Synergistic effect of n-3 PUFA and probiotic supplementation on bone loss induced by chronic mild stress through the brain–gut–bone axis

Journal of Functional Foods / 2023

17

Immunostimulatory activity of Lactococcus lactis LM1185 isolated from Hydrangea macrophylla

Food Sci Biotechnol. / 2022

16

Effect of orally administered heat-treated Lactobacillus plantarum LM1004 on the innate immune system: A randomized, placebo-controlled, double-blind study

Journal of Functional Foods / 2022

15

Investigation of Immunostimulatory Effects of Heat-treated Lactiplantibacillus plantarum LM1004 and its Underlying Molecular Mechanisms

Food Sci Anim Resour. / 2022

14

Hepatoprotective Effects of Streptococcus thermophilus LM1012 in the Methionine-Choline Deficient (MCD) Diet Induced Nonalcoholic Steatohepatitis Mice Model

the Korean Journal of Food and Nutrition / 2022

13

Anti-inflammatory potential of Lactobacillus reuteri LM1071 via eicosanoid regulation in LPS-stimulated RAW264.7 cells

J Appl Microbiol / 2022

12

Effects of Pediococcus pentosaceus strains isolated from three different types of Kimchi in ICR mice infected with Escherichia coli or Salmonella Typhimurium

Korean Journal of Agricultural Science  / 2022

11

Anti-inflammatory effects of Lactobacillus reuteri LM1071 via MAP kinase pathway in IL-1β-induced HT-29 cells

Journal of Animal Science and Technology / 2020

10

Lactobacillus fermentum promotes adipose tissue oxidative phosphorylation to protect against diet-induced obesity

Official journal of the Korean Society for Biochemistry and Molecular Biology / 2020

9

Hepatoprotective Effects of Streptococcus thermophilus LM1012 in Mice Exposed to Air Pollutants

Journal of Medicinal Food / 2020

8

Antiwrinkle and antimelanogenesis effects of tyndallized Lactobacillus acidophilus KCCM12625P

International Journal of Molecular Sciences / 2020

7

Oral Administration of β-Glucan and Lactobacillus plantarum Alleviates Atopic Dermatitis-Like Symptoms

J. Microbiol. Biotechnol / 2019

6

Micronized, Heat-Treated Lactobacillus plantarum LM1004 Alleviates Cyclophosphamide-Induced Immune Suppression

Journal of Medicinal Food / 2019

5

Micronized and Heat-Treated Lactobacillus plantarum LM1004 Stimulates Host Immune Responses Via the TLR-2/MAPK/NF-κB Signalling Pathway In Vitro and In Vivo

J. Microbiol. Biotechnol / 2019

4

Immunomodulatory Effects of β-1,3/1,6-glucan and Lactobacillus plantarum LM1004 on Atopic Dermatitis Models

Journal of the Learning Sciences
/ 2018

3

Enterococcus faecium FC-K Derived from Kimchi Is a Probiotic Strain That Shows Anti-Allergic Activity

J. Microbiol. Biotechnol / 2017

2

Antilisterial Bacteriocin from Lactobacillus rhamnosus CJNU 0519
Presenting a Narrow Antimicrobial Spectrum

Korean J. Food Sci. An. / 2015

1

Bifidobacterial Growth Stimulation by Lactobacillus casei via Whey Fermentation

Journal of Food Science and Nutrition / 2009